VESIcare Drug Interactions

Since many medicines can cause negative interactions, make sure to tell your healthcare provider about all other medicines you are taking before starting VESIcare. Drug interactions may occur if VESIcare is taken with anticholinergic drugs, protease inhibitors, or pramlintide. These VESIcare drug interactions may increase your risk for side effects, reduce the drugs' effectiveness, or increase the level of VESIcare in your blood.

 

VESIcare Drug Interactions: An Overview

VESIcare® (solifenacin succinate) can potentially interact with several other medicines. Some of the medicines that may lead to VESIcare drug interactions include:
 
  • Acetylcholinesterase inhibitor medications, such as:
 
 
  • Anticholinergic drugs, such as:
 
 
  • Certain antifungals or antibiotics, such as:
 
    • Clarithromycin (Biaxin®)
    • Erythromycin (Ery-Tab®)
    • Isoniazid (Nydrazid®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Telithromycin (Ketek®)
 
 
    • Alfuzosin (Uroxatral®)
    • Amoxapine
    • Apomorphine (Apokyn®)
    • Chloroquine (Aralen®)
    • Certain anesthetics
    • Certain antibiotics
    • Certain arrhythmia medications
    • Certain cancer medications
    • Certain nausea and vomiting medications
    • Certain phenothiazine or antipsychotic medications
    • Cisapride (Propulsid®)
    • Cyclobenzaprine (Flexeril®, Fexmid™)
    • Maprotiline (Ludiomil®)
    • Methadone (Dolophine®)
    • Octreotide (Sandostatin®)
    • Pentamidine (NebuPent®, Pentam®)
    • Ranolazine (Ranexa®)
    • Tacrolimus (Prograf®)
    • Vardenafil (Levitra®)
 
 
 
 
(VESIcare Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;