VESIcare Drug Interactions
VESIcare Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when VESIcare is combined with any of the drugs listed above.
Acetylcholinesterase Inhibitor Medications
Taking VESIcare with an acetylcholinesterase inhibitor can make both medications less effective. Your healthcare provider may need to monitor you more closely and adjust your dose of these medications to prevent interactions from occurring.
Combining an anticholinergic medication with VESIcare (which is also an anticholinergic medication) can increase your risk of VESIcare side effects, such as dry mouth, constipation, dry eyes, or difficulty passing urine.
Certain Antifungals or Antibiotics
Some antibiotic or antifungal medications may increase the level of VESIcare in your blood. Your healthcare provider may recommend that you take a lower VESIcare dosage if you are taking certain antibiotics or antifungals.
Both pramlintide and anticholinergic medications (including VESIcare) can slow down the movement of food through the digestive tract. Therefore, taking them together can increase the risk of constipation or nausea. Talk with your healthcare provider before combining these medications.
Protease inhibitors may increase the level of VESIcare in your blood. Your healthcare provider may recommend that you take a lower VESIcare dosage if you are taking a protease inhibitor.
Studies have suggested that high VESIcare dosages can increase the risk of an irregular heart rhythm called QT prolongation. Combining VESIcare with other QT-prolonging medications may increase this risk. Talk with your healthcare provider before taking these medications together.