Sanctura XR and Dry Mouth

There are several side effects of Sanctura XR (trospium XR), and dry mouth is the most common of these side effects. Clinical studies have shown that up to 11.1 percent of people taking Sanctura XR experienced a dry mouth. If you are taking Sanctura XR and dry mouth occurs, there are some things you can try, such as avoiding caffeinated drinks or sipping water frequently. If necessary, your healthcare provider may recommend other treatment options.

 

Does Sanctura XR Cause a Dry Mouth?

Yes, Sanctura® XR (trospium XR) can cause a dry mouth. In fact, a dry mouth is the most common Sanctura XR side effect. Sanctura XR is an anticholinergic medication, and like most anticholinergics, it often causes a dry mouth.
 
In studies, up to 11.1 percent of people taking the drug reported having a dry mouth, compared to only 3.7 percent of people taking a placebo (a "sugar pill" with no active ingredient).
 

Sanctura XR and Dry Mouth: Recommendations

If you are taking Sanctura XR and dry mouth becomes a problem, there are some things that you can do that may provide relief. Some of these suggestions include:
 
  • Avoiding drinks with caffeine, such as coffee, tea, and most sodas. Caffeine can dry out the mouth.
     
  • Chewing sugarless gum or sucking on sugarless hard candy to stimulate saliva flow; cinnamon- or mint-flavored candies are good choices.
     
  • Avoiding alcohol, because it can dry out the mouth.
     
  • Using a humidifier at night.
     
  • Being aware of spicy or salty foods, because they may cause pain in a dry mouth.
     
  • Sipping water or sugarless drinks frequently throughout the day and during meals. This will make chewing and swallowing easier; it may also improve the taste of food.
     
It is important to note that a severe or prolonged dry mouth can cause dental problems, as saliva helps to protect the teeth from decay. You may need special dental care in such situations.
 
(Sanctura XR and Dry Mouth Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;