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Enablex is used to treat symptoms of an overactive bladder, such as leaking accidents and frequent urination. By relaxing the bladder muscles, the drug helps reduce the frequent and uncontrollable bladder contractions that can result in symptoms. Enablex comes in tablet form and is taken once a day. Side effects can include dry mouth, constipation, and nausea.

What Is Enablex?

Enablex® (darifenacin) is a prescription medication approved for the treatment of overactive bladder. Specifically, it is approved to help treat the following overactive bladder symptoms:
  • Frequent urination (usually defined as needing to go more than eight times in 24 hours)
  • Sudden, frequent urges to urinate
  • Leaking accidents (known as urinary incontinence or urge incontinence).
(Click Enablex Uses for more information, including possible off-label uses.)

Who Makes Enablex?

It is made by Novartis Pharmaceuticals Corporation.

How Does It Work?

Enablex belongs to a group of medications known as antimuscarinics or anticholinergics. It works by blocking specific receptors in the bladder, called muscarinic receptors, which helps the muscles of the bladder to relax. Since an overactive bladder is often due to muscle contractions that are too frequent and uncontrollable, Enablex can help relieve many of the related symptoms.


Studies have shown Enablex to be effective in relieving many of the symptoms of an overactive bladder. In clinical studies, people who took the drug significantly reduced the frequency of wetting accidents. In addition, people who took it used the bathroom less frequently and were able to pass more urine each time (the frequent muscle contractions of an overactive bladder usually prevent the bladder from holding a normal amount of urine).

Enablex -- Medication Information

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