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Enablex Warnings and Precautions

Before beginning treatment with Enablex, warnings and precautions for the drug should be discussed with your healthcare provider. Tell him or her if you have liver disease, digestive problems, or glaucoma before starting the medication. Enablex may also worsen glaucoma, decrease your ability to sweat, and slow the digestive system. Knowing Enablex warnings and precautions beforehand can help minimize these risks.

Enablex: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Enablex® (darifenacin) if you have:
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Enablex Warnings and Precautions

Warnings and precautions to be aware of prior to taking Enablex include the following:
  • In rare cases, Enablex can cause life-threatening swelling of the mouth, lips, tongue, or throat. If this happens, seek immediate medical attention.


  • This medication may make glaucoma worse. If you have glaucoma and take Enablex, your healthcare provider may need to monitor you more closely.


  • Enablex can slow the digestive system. This can cause problems, especially for people who already have a slow digestive system due to myasthenia gravis, ulcerative colitis, or other problems.
  • The liver helps to remove Enablex from your body. If you have liver disease, you may require extra monitoring by your healthcare provider and may need to take a lower dosage.


  • Enablex has been reported to cause a variety of side effects affecting the central nervous system. Such side effects might include headaches, confusion, hallucinations, and severe drowsiness. Let your healthcare provider know if you develop any such side effects. 


  • Enablex can cause blurred vision, dizziness, and drowsiness. Be sure that you know how the medication affects you before driving or operating heavy machinery.
  • Enablex can decrease your ability to sweat, which may increase your risk of heat stroke. Be sure to stay well hydrated in the heat.
  • Enablex may potentially interact with a number of other medications (see Enablex Drug Interactions).
  • Enablex is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not known (see Enablex and Pregnancy).
  • It is not known whether Enablex passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Enablex and Breastfeeding).

Enablex -- Medication Information

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