Enablex Drug Interactions (Cont.)

Enablex Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Enablex is combined with any of the drugs listed above.
 
Acetylcholinesterase Inhibitor Medications
Taking Enablex with an acetylcholinesterase inhibitor can make both medications less effective. Your healthcare provider may need to monitor you more closely and adjust your dose of these medications to prevent interactions from occurring.
 
Anticholinergic Drugs
Combining an anticholinergic medication with Enablex (which is also an anticholinergic medication) can increase your risk of Enablex side effects, such as dry mouth, constipation, dry eyes, or difficulty passing urine.
 
Certain Antifungals or Antibiotics
Some antibiotic or antifungal medications may increase the level of Enablex in your blood. Your healthcare provider may recommend that you take a lower Enablex dosage if you are taking certain antibiotics or antifungals.
 
Flecainide
Enablex may increase the level of flecainide in your blood, possibly leading to dangerous flecainide side effects. Check with your healthcare provider before using these medications together.
 
Nefazodone
Nefazodone can increase the level of Enablex in your blood. Your healthcare provider may recommend that you take a lower dose of Enablex if you are taking nefazodone.
 
Pramlintide
Both pramlintide and anticholinergic medications (including Enablex) can slow down the movement of food through the digestive tract. Taking them together can increase the risk of constipation or nausea. Talk with your healthcare provider before combining these medications.
(Enablex Drug Interactions Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;