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Enablex and Constipation

In clinical studies of Enablex, constipation appeared to be one of the most common side effects. Up to 21.3 percent of people taking the highest Enablex dosage and 14.8 percent of those taking the lower dosage experienced constipation. If you are taking Enablex and constipation develops, talk to your healthcare provider or try making dietary and lifestyle changes.

Does Enablex Cause Constipation?

Enablex® (darifenacin) is a prescription medication used to treat overactive bladder. Like all anticholinergic medications, Enablex often causes constipation. In fact, constipation is considered a "classic" side effect of such drugs.

How Common Is Constipation With Enablex?

Before medicines are approved for use in the United States, they must go through several clinical studies. In these studies, many people are given a particular medicine, while others are given a placebo (a "sugar pill" with no active ingredient). In these studies, potential side effects in both groups are carefully documented. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group taking the placebo.
In clinical studies, up to 21.3 percent of people taking the highest Enablex dosage (15 mg daily) experienced constipation, compared to 6.2 percent of people taking the placebo. It is important to note that the lower dosage (7.5 mg daily) caused constipation in only 14.8 percent of people.

Enablex and Constipation: Final Thoughts

If you develop constipation on Enablex, talk to your healthcare provider. You can also try making a few dietary and lifestyle changes. Increasing fiber in your diet or adding bran to your food may be helpful. Drinking plenty of fluids and getting regular exercise can also help. It is important to understand that severe constipation can be quite serious; do not hesitate to talk with your healthcare provider if you are experiencing severe constipation due to Enablex.
(Click Constipation Treatment for more recommendations on treating constipation.)

Enablex -- Medication Information

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