Detrol and Pregnancy
Animal studies on Detrol and pregnancy suggest that the medication may not be safe for pregnant women. When the drug was given to pregnant mice, the risk for birth defects, miscarriages, and low fetal weight was increased. Since animals do not always respond to drugs the same way that humans do, however, Detrol can be prescribed to pregnant women if the benefits outweigh the risks.
Detrol® (tolterodine tartrate) is a prescription medication approved for treating an overactive bladder. It may not be safe for use in pregnant women. In animal studies, the drug caused problems when used during pregnancy.
The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but that do appear to cause harm to the fetus in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
When given to mice in high dosages, Detrol increased the risk of birth defects, miscarriages, and low fetal weight. When high doses were given to pregnant rabbits, however, no problems occurred. No studies have evaluated the drug in pregnant women.
It is important to note that animals do not always respond to medicines the same way that humans do. Therefore, a pregnancy Category C medicine may be given to a pregnant woman if her healthcare provider believes that the benefits to the woman outweigh any possible risks to the unborn child.
Be sure to let your healthcare provider know if you are pregnant or are thinking of becoming pregnant while taking Detrol. He or she will consider both the benefits and risks of using Detrol during pregnancy before making a recommendation in your particular situation.